Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart Surgery

• Status: Suspended
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the wound infusion of articaine for treatment of acute post-sternotomy pain in a placebo-controlled manner using a prospective and randomized design and an active control (bupivacaine)

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Helsinki University Central Hospital
• Treatments: Anesthetics; Anesthetics, Local; Bupivacaine; Carticaine

Criteria

Inclusion Criteria:

• elective procedure

• open heart surgery

• aortic valve surgery

• mitral valve surgery

• atrial septal defect repair surgery

• intracardial myxoma removal surgery

Exclusion Criteria:

• local anesthetic allergy

• sulphide allergy

• asthma

• pregnant women

• neurological disease (TIA excluded)

• congestive heart failure

• left ventricle ejection fracture under 0.3

• liver failure

• diabetes mellitus with documented polyneuropathy

• chronic pain condition

• mother tongue not finnish or swedish

• patients, who do not agree blood transfusions