Comparison of the Efficacy of Levofloxacin-based Sequential Therapy and Triple Therapy as Second Line Therapy

• Status: Unknown status
• Trial end date: 2016-04-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare the efficacy and tolerability of levofloxacin-based sequential therapy and triple therapy in the second line therapy for those who fail from one eradication therapy

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Taiwan University Hospital
• Collaborator: E-DA Hospital
• Treatments: Amoxicillin; Dexlansoprazole; Lansoprazole; Levofloxacin; Ofloxacin

Criteria

Inclusion Criteria:

• H. pylori infected patients who failed from first line therapy will be eligible in this study

Exclusion Criteria:

• Patients were excluded from the study if any one of the following criteria was present:

• children and teenagers aged less than 20 years,

• history of gastrectomy,

• gastric malignancy, including adenocarcinoma and lymphoma,

• previous allergic reaction to antibiotics (amoxicillin, metronidazole, levofloxacin) and PPI (lansoprazole),

• contraindication to treatment drugs,

• pregnant or lactating women, or

• severe concurrent disease