Comparison of the Efficacy of Intravenous Dexketoprofen and Paracetamol in the Treatment of Sore Throat

• Status: Completed
• Trial end date: 2018-07-30
• Target enrollment: 0
• Participant gender: All

Summary

Currently, paracetamol and nonsteroidal antiinflammatory drugs are widely used by emergency physicians in Turkey for the treatment of sore throat. The objective of the study is compare the efficacy of intravenous dexketoprofen and paracetamol in the treatment of the pain in patients presenting to the emergency department with sore throat

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pamukkale University
• Treatments: Acetaminophen; Dexketoprofen trometamol

Criteria

Inclusion Criteria:

• Patients with sore throat less than three days

• Patients with at least one of the following:

• According to the throat pain scale, patients with moderate-severe pain,

• At least 1 upper respiratory tract infection (URTI) symptom according URTI questionare,

• Objective findings of pharyngeal inflammation (Tonsillopharyngitis evaluation score ≥5),

• 60 mm or more according to the sore throat sensitivity scale (STSS),

• 50 mm and above according to difficulty swallowing scale (DSS),

• 33 mm and above according to the swollen throat scale (SwoTS)

Exclusion Criteria:

• Patients use analgesic last 12 hours

• Patients with severe liver, kidney,pulmonary and cardiac heart failure

• To be Pregnancy and breast-feeding Patients of childbearing age who are not using a birth control method

• Patients with an allergy trait (paracetamol and dexketoprofen) Illiterates

• Patients with vision problems

• Patients use antibiotics last 24 hours

• Patients use kinolons last 7 days

• Patienst use lozange,throat spray or menthol containing products last 4 hours

• Hemodynamically unstable patients,Patients with renal transplantation

• Patients with glucose 6 phosphate dehydrogenase (G6PD) deficiency

• Patients with non-controlled hypertension

• Patients with a history of cerebrovascular disease

• Patients with Wolff-Parkinson-White syndrome or accompanying arrhythmias associated with conductive stimulus delivery in the heart