Comparison of the Efficacy and Safety of Ivermectin to Permethrin

• Status: Completed
• Trial end date: 2005-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Comparison of the efficacy and safety of a single administration of ivermectin to a single administration of permethrin for the treatment of scabies

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Ghent
• Treatments: Ivermectin; Permethrin

Criteria

Inclusion Criteria:

At least one of the following inclusion criteria:

• Scabies tunnels

• Positive microscopic examination (acarids, faeces or ova)

At least two of the three following inclusion criteria:

• Non-specific injuries with a typical distribution pattern

• Serious itching which increases during the night

• Family or contacts with similar complaints

Exclusion Criteria:

• Treatment for scabies < 4 weeks ago

• Treatment with corticoids < 1 week ago

• Pregnancy

• Breast-feeding

• HIV

• Serious immunodepressive patients

• Sensitivity or allergy to one of the components of the study medication

• Damage of the central nerve system