Comparison of the Duration of Ropivacaine Combined With Dexmedetomidine or Dexamethasone on Paravertebral Block

• Status: Completed
• Trial end date: 2019-11-18
• Target enrollment: 0
• Participant gender: All

Summary

This study was a prospective, randomized, controlled, and double-blind trial. Major assessments were made during the operation and 48 h postoperatively.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: China Medical University, China
• Treatments: Analgesics; BB 1101; Dexamethasone; Dexamethasone acetate; Dexmedetomidine; Ropivacaine

Criteria

Inclusion Criteria:

• (1) age 18 to 65 years,

• (2) scheduled to undergo video-assisted thoracic surgery,

• (3) American Society of Anesthesiologists risk classification I-II.

Exclusion Criteria:

• (1) patient refusal;

• (2) known hypersensitivity to the study medication (ropivacaine);

• (3) long-term use of opioids;

• (4) liver or renal insufficiency;

• (5) a history of psychiatric or neurological disease;

• (6) deafness;

• (7) regular use of acetaminophen, nonsteroidal anti-inflammatory drugs, corticosteroids, or antiemetics; and

• (8) a preoperative Pittsburgh Sleep Quality Index (PSQI) global score higher than 6.