Comparison of Valsartan With Amlodipine in Hypertensive Patients With Glucose Intolerance
Status:
Completed
Trial end date:
2013-04-01
Target enrollment:
Participant gender:
Summary
Various guidelines recommended angiotensin converting enzyme (ACE) inhibitors or angiotensin
Ⅱ receptor-1 blockers (ARBs) for hypertensive patients with diabetes on the basis of the
cardiac- and reno-protective effects of these drugs. However, these recommendations could not
be extrapolated to Japanese patients, because Japan has been known as a country with a low
incidence of coronary artery disease and a high incidence of cerebrovascular disease.
Furthermore, calcium channel blockers (CCBs) also were protective against renal function as
well as ACE inhibitors in Japanese diabetic hypertensive patients. This study will test
whether ARBs or CCBs are superior in treating Japanese diabetic hypertensive patients.