Comparison of Two Pharmacological Treatments of Pedophilia

• Status: Terminated
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: Male

Summary

Sexual abuse committed on children is a major public health problem because of its frequency and its severe consequences on the mental health of victims.

Objective: to compare the therapeutic efficacy of cyproterone acetate (CPA) and leuprolide, with the hypothesis that leuprolide will be more effective.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
• Collaborators: Assistance Publique - Hôpitaux de Paris; Ministry of Health, France; Ministry of Higher Education and Research, France
• Treatments: Cyproterone; Cyproterone Acetate; Leuprolide

Criteria

Inclusion Criteria:

• clinical diagnosis of pedophilia

• high frequency of sexual urges and deviant behavior as demonstrated by a score equal to 8 on the scale of Rösler & Witztum (Rösler & Witztum, 1998) ;

• age: 18-60 years

• informed consent

Exclusion Criteria:

• IQ<70

• schizophrenia, schizoaffective disorder, or delusional disorder

• already receiving one of the tested drugs

• contraindication for one of the tested drugs

• no current or planned incarceration