Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

There will be two groups in this study: one group will be given the standard infusion of naloxone, a drug which helps reduce side effects from opioids needed after surgery, and the other group will receive a higher dose. The trial is designed to determine if a higher dose of naloxone infusion will reduce side effects from opioid therapy in patients who have undergone spine fusion for scoliosis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Mercy Hospital Kansas City
• Treatments: Naloxone

Criteria

Inclusion Criteria:

• Idiopathic scoliosis requiring spine fusion surgery

• Age 10-21 years

Exclusion Criteria:

• Inability to understand PCA instructions

• Allergy to: morphine, hydromorphone, fentanyl, naloxone, or diphenhydramine

• Chronic opioid therapy > 2 months

• Non-English speaking