Overview

Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome--Pediatric Heart Network

Status:
Completed

Trial end date:
2014-02-01

Target enrollment:

Participant gender:

Summary

Marfan syndrome is a hereditary connective tissue disorder. Many individuals with this condition die because of the associated heart and blood vessel abnormalities. This study will compare the effectiveness of two medications, losartan and atenolol, at slowing aortic root enlargement in individuals with Marfan syndrome.

Phase:

Phase 3

Details

Lead Sponsor:

HealthCore-NERI
New England Research Institutes

Collaborators:

FDA Office of Orphan Products Development
National Heart, Lung, and Blood Institute (NHLBI)
National Marfan Foundation

Treatments:

Angiotensin Receptor Antagonists
Atenolol
Losartan