Overview

Comparison of Two Application Techniques for LET Gel

Status:
Completed
Trial end date:
2019-11-12
Target enrollment:
0
Participant gender:
All
Summary
Comparison of anesthetic efficacy of Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel (LET) applied three times for 10 minutes each time vs. once for 30 minutes prior to suturing simple lacerations in children aged 7-17 years.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Collaborators:
Children's Hospital of Orange County
Children’s Hospital of Orange County
Treatments:
Epinephrine
Epinephryl borate
Lidocaine
Racepinephrine
Tetracaine
Criteria
Inclusion Criteria:

- Simple <= 3cm lacerations requiring suturing (as decided by clinician care providers)

- Plan to suture with simple interrupted sutures

Exclusion Criteria:

- Lacerations involving the hands, feet, genitals, tongue, mucus membranes, nose, ears,
or occurring over joints

- Patients whose primary language was neither English nor Spanish

- Developmentally delayed or disabled patient such that they were unable to give a pain
score

- Patients requiring procedural sedation or anxiolysis with oral or intranasal midazolam