Comparison of Two Antimicrobial Therapy Duration for Spondylodiscitis
Status:
Completed
Trial end date:
2013-04-01
Target enrollment:
Participant gender:
Summary
Duration of antimicrobial therapy for spondylodiscitis is not standardized; it could vary
from 6 weeks to several months depending on the medical habits. The study hypothesis is that
a 6 weeks antimicrobial therapy is not inferior to a 12 weeks.
We run a prospective multi-centric, non inferiority open label trial, randomised in two
parallel groups.
The main objective is to compare the efficacy of two durations of antibiotherapy, 6 weeks
versus 12 weeks, on the rate of cure in this indication.
The study concerns 400 patients more than 18 years, 70 centres in France are involved.
The duration of the study is 4 years.