Overview

Comparison of Treatment Success of Botox Injection in the Internal Sphincter Versus Isosorbidedinitrate Ointment in Patients With an Anal Fissure

Status:
Completed

Trial end date:
2006-03-01

Target enrollment:

Participant gender:

Summary

The standard treatment of anal fissure in the netherlands (ISDN ointment) is being compared to a relatively new treatment (injection of Botox in the internal anal sphincter). The study hypothesis is that after 4 months, Botox has healed more patients than ISDN. The comparison is done blinded for the surgeon and the patient.

Phase:

Phase 4

Details

Lead Sponsor:

Onze Lieve Vrouwe Gasthuis

Treatments:

abobotulinumtoxinA
Botulinum Toxins, Type A
incobotulinumtoxinA
Isosorbide
Isosorbide Dinitrate
Isosorbide-5-mononitrate
onabotulinumtoxinA