Comparison of Topical Versus Intravenous Tranexamic Acid in TKA
Status:
Completed
Trial end date:
2015-10-01
Target enrollment:
Participant gender:
Summary
Previous studies in both the cardiovascular and orthopedic study have shown tranexamic acid
(TXA) reduces blood loss and post-operative blood transfusion rate largely without major
complications . In addition, many meta-analyses have confirmed these results . However, there
is little information about comparison among the different routes of TXA administration in
TKA. Therefore, this study has been designed to determine which administration route of TXA
is more effective and safety.