Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of our study is to assess the effect of topical vasoconstriction (cocaine 4% versus adrenaline 1/1000) on the surgical field during endoscopic sinus surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Marc Tewfik
• Treatments: Cocaine; Epinephrine; Epinephryl borate; Pharmaceutical Solutions; Racepinephrine

Criteria

Inclusion Criteria:

• Patients older than 18 years undergoing bilateral ESS for chronic sinusitis.

Exclusion Criteria:

• Patients with heart disease

• History of bleeding diathesis

• Patients with untreated or poorly controlled high blood pressure

• Aspirin, anticoagulant or natural herbal medication usage in the last 4 weeks

• Hypersensitivity to adrenaline or cocaine

• Significant asymmetry between the right and left side disease extent as determine by findings on their pre-operative CT scan and nasal endoscopy.