Comparison of Ticagrelor Pharmacokinetics and Pharmacodynamics in STEMI and NSTEMI Patients
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
The purpose of the PINPOINT study is to compare pharmacokinetics (PK) and pharmacodynamics
(PD) of ticagrelor in ST-elevation myocardial infarction (STEMI) and non-ST-elevation
myocardial infarction (NSTEMI) patients designated to invasive strategy. Data regarding
comparison of PK and antiplatelet action of ticagrelor in STEMI and NSTEMI are sparse.
Recommended dosing regimens of ticagrelor are identical for both STEMI and NSTEMI, although
it is not known whether PK and PD features of ticagrelor are uniform in these patients.