Comparison of Three Different Treatment Regimes in Early Rheumatoid Arthritis: A Randomized Open-labelled Trial
Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
Many studies have been conducted to evaluate the role of pulse steroids in early rheumatoid
arthritis (RA) but no consensus exists. The aim of this study is to study the efficacy of
various treatment regimens in early RA. Methods: This is a randomized open-labeled trial.
Patients were randomised into three groups. In group A, patients were treated with single
drug (methotrexate 15 mg/wk). The patients in Group B were treated with a combination of
DMARDS (Methotrexate, sulfasalazine and hydroxychloroquine). The patients in Group C received
combination therapy as in group B and 3 pulses of methylprednisolone intravenously.
Phase:
Phase 3
Details
Lead Sponsor:
All India Institute of Medical Sciences, New Delhi