Comparison of Three Deep Sedation Strategies for Pulsed-Field Ablation
Status:
NOT_YET_RECRUITING
Trial end date:
2025-10-30
Target enrollment:
Participant gender:
Summary
This prospective, randomized, parallel, single-center study aims to evaluate the effectiveness and safety of three deep sedation strategies in patients undergoing pulsed-field ablation (PFA) for atrial fibrillation (AF). The primary endpoint is the proportion of patients achieving adequate sedation (Ramsay sedation score 3) during ablation. Secondary outcomes include intraoperative sedation difficulty, operator satisfaction, patient recall of intraoperative pain, perioperative hemodynamic events, and the need for intraoperative interventions.