Comparison of Therapy in Treatment of Patients With Helicobacter Pylori Infection: Concomitant Versus Hybrid Therapy.
Status:
Completed
Trial end date:
2019-10-15
Target enrollment:
Participant gender:
Summary
The aim of the study is to compare the effectiveness of two therapeutic protocols in the
treatment of Helicobacter pylori infection.
The hypothesis of our research is that the two therapeutic options (hybrid and concomitant
therapy) will be equally successful in the treatment of Helicobacter pylori infection. In
other words, in both therapeutic groups we expect successful treatment of Helicobacter pylori
infection in or more than 90 % of patients.
In other studies, both therapeutic options have the same efficacy in treating H. pylori
infection. On the other had there are no studies available in Croatia to compare the
effectiveness of these therapeutic options so far, which is the main objective of our
research. The secondary goals of our study will be: the existence of differences in the
occurrence of possible side effects, as well as the compliance between patients in both
therapeutic options. It is also our aim to compare the quality of life of patients with
Helicobacter pylori infection before and after treatment, via a questionnaire that is common
for this purpose.
The study is expected to include a total of 120 patients (60 patients in each therapy group),
and the planned duration is 12 months.
Phase:
N/A
Details
Lead Sponsor:
Antonio Mestrovic
Collaborators:
University Hospital of Split University of Split, School of Medicine