Comparison of TIVA (Total Intravenous Anesthesia) and TIVA Plus Palonosetron in Preventing Postoperative Nausea and Vomiting

• Status: Completed
• Trial end date: 2011-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

A total intravenous anesthesia (TIVA) is a useful anesthetic technique that reduces the incidence of postoperative nausea and vomiting (PONV).

Investigator hypothesized the incidence of PONV can be further reduced when palonosetron is added to TIVA.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Incheon St.Mary's Hospital
• Treatments: Anesthetics; Palonosetron

Criteria

Inclusion Criteria:

• ASA Physical Status 1 or 2

• Elective gynaecological laparoscopic surgery of ≥ 1h duration

Exclusion Criteria:

• Anti-emetics, steroids, or psychoactive medications within 24 h of study initiation

• Vomiting or retching in the 24 h preceding surgery

• Cancer chemotherapy within 4 weeks or emetogenic radiotherapy within 8 weeks before study entry

• Ongoing vomiting from gastrointestinal disease