Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section

• Status: Terminated
• Trial end date: 2021-03-20
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this prospective single center, randomized study is to determine if ultrasound guided Transversus Abdominis Plane (TAP), Quadratus Lumborum (QL), and Erector Spinae Plane (ESP) blocks decrease opioid consumption in subjects undergoing elective cesarean section.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Duke University
• Treatments: Epinephrine; Epinephryl borate; Racepinephrine; Ropivacaine

Criteria

Inclusion Criteria:

1. American Society of Anesthesiologists (ASA) Physical Status 1-3

2. Age greater than or equal to 18 years

3. Scheduled for elective cesarean section

4. English speaking

Exclusion Criteria:

1. ASA Physical Status 4-5

2. Diagnosis of chronic pain

3. Chronic opioid use (opioid use in the past 3 months)

4. Preoperative use of SSRIs (Celexa, Lexapro, Prozac, Paxil), SNRIs (Cymbalta, Effexor), gabapentin, or pregabalin (Lyrica)

5. Inability to cooperate with or understand protocol

6. Inability to communicate pain scores or need for analgesia

7. Infection at the site of block placement

8. Intolerance or allergy to local anesthetics

9. Neurologic deficit or disorder

10. Blood thinning disorder or taking anticoagulant medication

11. BMI > 50 kg/m2

12. Suspected or known addiction to or abuse of illicit drug(s), prescription medicine(s), or alcohol within the past 2 years

13. Uncontrolled anxiety, schizophrenia, or other psychiatric disorder that, in the opinion of the investigator, may interfere with study assessments or compliance

14. Current or historical evidence of any clinically significant disease or condition that, in the opinion of the investigator, may increase the risk of surgery or complicate the subject's postoperative course