Overview

Comparison of Sequential or Concomitant Therapy for Helicobacter Pylori Infection

Status:
Completed
Trial end date:
2010-06-01
Target enrollment:
Participant gender:
Summary
Helicobacter pylori is a bacteria that infects the lining of the stomach and is associated with ulcers. Helicobacter pylori may also increase the long-term risk of developing certain forms of gastric cancer. Curing this infection generally requires that patients take 2 or more antibiotic medications and a stomach acid suppressing medication for about two weeks. Current treatments do not always cure the infection and a new treatment is being tested in this study. The drugs involved in the new 4 drug treatment have been widely used for treatment of this infection. It remains unknown what is the best and most cost effective way to give them. This study will compare three different ways of using these drugs. Subjects must have active Helicobacter pylori infection in order to participate in this study.
Phase:
Phase 4
Details
Lead Sponsor:
Kaohsiung Veterans General Hospital.
Collaborator:
Baylor College of Medicine
Treatments:
Amoxicillin
Clarithromycin
Esomeprazole
Metronidazole