Overview

Comparison of SAR341402 to NovoLog in Adult Patients With Type 1 Diabetes Mellitus Also Using Insulin Glargine

Status:
Completed
Trial end date:
2020-07-08
Target enrollment:
Participant gender:
Summary
Primary Objective: To demonstrate similarity in pharmacokinetics (PK) of SAR341402 and NovoLog after 4x4-week periods of alternating administration of SAR341402 and NovoLog compared to 16-week continuous use of NovoLog in participants with Type 1 diabetes mellitus also using insulin glargine. Secondary Objectives: - To compare the effects of alternating administration of SAR341402 and NovoLog with continuous use of NovoLog on immunogenicity. - To evaluate the safety of alternating administration of SAR341402 and NovoLog versus continuous use of NovoLog. - To compare other PK parameters between the two treatment arms (alternating administration of SAR341402 and NovoLog and continuous use of NovoLog).
Phase:
Phase 3
Details
Lead Sponsor:
Sanofi
Treatments:
Insulin
Insulin Aspart
Insulin degludec, insulin aspart drug combination
Insulin Glargine
Insulin, Globin Zinc
Insulin, Long-Acting