Comparison of Propranolol and Venlafaxine in Treatment of Vestibular Migraine
Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
The presented study aims to compare effectivity of propranolol with effectivity of
venlafaxine in escalating dose in subjects with vestibular migraine (VM) over a period of 12
weeks. The study population consisted of subjects diagnosed definite VM according to criteria
of Bárány Society and Migraine Classification Subcommittee of the International Headache
Society (IHS). Effectivity of therapy was measured by Dizziness Handicap Inventory (DHI),
number of vertiginous attack of last month and visual analogue scale (VAS) reported dizziness
related Quality of Life (QOL). Beck Anxiety Inventory (BAI) and Beck Depression Inventory
(BDI) were also used to determine psychiatric improvement played role in response to therapy
in venlafaxine treatment arm.