Comparison of Propofol, Propofol-remifentanil and Propofol-ketamine Anesthesia During Electroconvulsive Therapy
Status:
Completed
Trial end date:
2017-03-01
Target enrollment:
Participant gender:
Summary
Electroconvulsive therapy (ECT) is a common treatment method used in severe depression and
other psychiatric diseases. Currently, most ECT procedures are carried out with muscle
paralysis under general anaesthesia. The anticonvulsant properties of sedative and hypnotic
drugs used during general anaesthesia may reduce the efficacy of ECT. It is important to
establish an accurate balance between adequate anaesthesia depth and optimal seizure
duration.
We aimed to compare the effectiveness of three anaesthetic regimens (propofol alone, propofol
with remifentanil and propofol with ketamine), with respect to seizure duration and seizure
quality in patients undergoing electroconvulsive therapy.