Comparison of Prilosec OTC® Versus Zegerid® for Gastric Acid Suppression

• Status: Completed
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare Prilosec OTC® and Zegerid® in their effects on gastric acid suppression.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Procter and Gamble
• Treatments: Omeprazole; Omeprazole, sodium bicarbonate drug combination

Criteria

Inclusion Criteria:

• Normal subjects who are 18-65 years of age;

• Non-childbearing potential females or those using birth control

Exclusion Criteria:

• History of significant GI disease

• Any significant medical illness

• History of hypersensitivity, allergy or intolerance to omeprazole or other proton pump inhibitors;

• Currently using GI medications

• GI disorder or surgery leading to impaired drug absorption