Comparison of Postoperative Outcome After Sevoflurane and Propofol Anaesthesia
Status:
Completed
Trial end date:
2018-06-01
Target enrollment:
Participant gender:
Summary
As the investigators know, postoperative cognitive dysfunction (POCD) is a fairly
well-documented clinical phenomenon, which affect patients' short-term and long-term outcome.
Most patients will receive general anesthesia and cardiopulmonary bypass (CPB) during cardiac
valvular surgery. Inhalation sevoflurane based and propofol based anesthesia are most
commonly used strategy for general anesthesia. At present, it was unknown that which one is
better in providing cerebral protection effect for patients undergoing cardiac valvular
surgery with CPB. The current study aimed to explore the possible difference.