Comparison of Postoperative Anti-nausea and Vomiting Effect Between Glycopyrronium and Ondansetron

• Status: Recruiting
• Trial end date: 2022-08-31
• Target enrollment: 0
• Participant gender: All

Summary

To compare the anti-nausea and vomiting effect between glycopyrronium and ondansetron for patients receiving elective surgery under general anesthesia. Based on this study we intend to explore the feasibility of using glycopyrronium to prevent postoperative nausea and vomiting.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Second Affiliated Hospital of Chongqing Medical University
• Collaborators: ChongGang General Hospital; Chongqing Health Center for Women and Children; Chongqing Liangping District People's Hospital; Chongqing Medical University; Chongqing Public Health Medical Center; Chongqing University Jiangjin Hospital; Chongqing Yongchuan District People's Hospital; Dianjiang People's Hospital of Chongqing; Jiulongpo People's Hospital of chongqing; People's Hospital of Pengshui County; The First People's Hospital Of Chongqing Liang Jiang New Area; The Ninth People's Hospital of Chongqing; The People's Hospital of DAZU ，Chongqing; The People's Hospital of Nanchuan; The People's Hospital of Qijiang District，Chongqing; The People's Hospital of Tongliang District， Chongqing city; The People's Hospital of Yubei District of Chongqing city; University-Town Hospital of Chongqing Medical University; West China Hospital; Xiangya Hospital of Central South University; Yunyang people's Hospital
• Treatments: Glycopyrrolate; Ondansetron

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists classification I-II

• Receive general anesthesia

• Voluntarily receive postoperative intravenous controlled analgesia

Exclusion Criteria:

• Puerpera or lactation women

• Allergy or existing contraindication to glycopyrronium and ondansetron

• Participate in other clinical drug trials within three months

• Can not follow with the study procedure