Overview

Comparison of Phenylephrine and Ephedrine in the Treatment of Hemodynamic Disorders After Spinal Anesthesia in the Elderly

Status:
Unknown status
Trial end date:
2020-04-01
Target enrollment:
0
Participant gender:
All
Summary
Spinal anesthesia is often used for lower limb surgery in elderly. Hypotension is a side effect of spinal block. In this study, intravenous ephedrine and phenylephrine will be compared with each other to prevent spinal anesthesia-induced hypotension, which is defined in absolute terms as a systolic blood pressure < 100 mmHg or in relative terms as a 20% fall of systolic blood pressure from baseline.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Medical University of Warsaw
Treatments:
Ephedrine
Oxymetazoline
Phenylephrine
Pseudoephedrine
Criteria
Inclusion Criteria:

- elderly (age more than 65 years)

- hip fracture scheduled for lower limb surgery under spinal anesthesia

- spinal anesthesia

Exclusion Criteria:

- contraindications to spinal anesthesia

- participant refusal

- age less than 65

- bradycardia (heart rate less than 60)

- participants unable to give consent or inability to communicate