Comparison of Pain of Conventional to Buffered Local Anesthesia During Injection in Pediatric Dental Patients
Status:
Completed
Trial end date:
2013-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the effectiveness of buffered local anesthesia
injections to numb the gums and teeth during dental treatment. Adjusting the pH of lidocaine
with sodium bicarbonate may reduce the pain of injection for both adults and children. In
this study, the investigators will compare two local anesthetic preparations, a buffered
anesthetic and the conventionally available anesthetic, for pain upon injection.
Hypothesis: Anesthetic buffered to physiologic pH will result in a less painful injection
compared to the acidic alternative used in most dental offices. This can be demonstrated by
comparing two local anesthetic preparations, a buffered anesthetic and the conventionally
available anesthetic, for pain upon injection.
Phase:
Phase 4
Details
Lead Sponsor:
University of California, San Francisco
Treatments:
Anesthetics Anesthetics, Local Epinephrine Lidocaine