High blood pressure (Hypertension) is extremely common and is a major cause of heart disease,
kidney disease and stroke. One in three of the UK (United Kingdom) population will require
treatment for hypertension at some point in their lives. A healthy lifestyle alone is often
not enough to control blood pressure, and drug treatment is usually required. Although a wide
variety of drugs are available to treat hypertension, choosing the right kind of tablet or
combination of tablets for individual patients is a problem, and therefore many people have
poor blood pressure control.
Hypertension treatment within the UK is currently selected according to age and self-defined
ethnicity (SDE). There are limitations to this approach which include wide variability in the
response to hypertension drug classes between people. There is also uncertainty about
selecting hypertension drugs for ethnic minorities other than those of African/Caribbean
ancestry, for example, South Asians because of a lack of information from trials. In the AIM
HY-INFORM study the investigators are looking to recruit equal number of black/caribbean,
south asian and white european participants to be able to compare differences in hypertension
treatments and ethnicity.
The primary objective of this study is to determine if the response to antihypertensive drugs
differs by self defined ethnicity.
Phase:
Phase 4
Details
Lead Sponsor:
Cambridge University Hospitals NHS Foundation Trust