Comparison of Opioid Based and Opioid Free Anaesthesia in Transsphenoidal Surgery

• Status: Completed
• Trial end date: 2017-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study has been planned to compare the effect of opioid free anaesthesia using dexmedetomidine and ketamine with opioid based anaesthesia using fentanyl in maintaining the intraoperative hemodynamic stability and recovery characteristics in patients undergoing Transsphenoidal surgery of pituitary tumors.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Postgraduate Institute of Medical Education and Research
• Treatments: Dexmedetomidine; Fentanyl; Ketamine

Criteria

Inclusion Criteria:

• patients suffering significant pituitary adenocarcinomas posted for transsphenoidal resection of tumor

• age group between 18 to 65 yr

• Both males and females

• ASA physical status 1 to 2

Exclusion Criteria:

• pts taking opioid for chronic pain

• Pregnant or nursing woman

• Preoperative GCS <15

• HR<50/min

• Patients with allergies to study medication

• Patients with psychiatric disorder

• Patients with unstable cardiorespiratory disorder

• Patients with hepatic and renal insufficiency