Comparison of Meperidine and Fentanyl on Pain Scale and QOL in Brachytherapy

• Status: Completed
• Trial end date: 2014-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

Purpose: To compare the pain level and quality of life of the two sedation regimens consisting of diazepam in combination with meperidine or fentanyl.

Materials and methods: A total of 40 patients (160 sessions of brachytherapy), unselected brachytherapy out patients at Chulabhorn Hospital, Thailand were enrolled with informed consent and randomized to receive meperidine or fentanyl. Data of perceived pain (according to standard 10-cm visual analog scales [VAS]), and perceived Quality of life (EQ-5D) were collected. Patients and all brachytherapy staffs directly involved with the procedure were blinded about the drug used.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chulabhorn Cancer Center
• Treatments: Fentanyl; Meperidine

Criteria

Inclusion Criteria:

• Aged 20 years old or older,

• Diagnosed with cervical cancer

• On course of external Radiation therapy

• Treated with brachytherapy 4 times.

Exclusion Criteria:

• Pregnant

• Previously underwent intracavitary brachytherapy

• Illiterate