Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant Schizophrenia

• Status: Completed
• Trial end date: 2020-06-30
• Target enrollment: 0
• Participant gender: All

Summary

The proposed study will be conducted to compare the efficacy of maintenance ECT (M-ECT) vs Clozapine in treatment resistant schizophrenia (TRS) in terms of change in psychopathology measures and cerebral hemodynamics.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: All India Institute of Medical Sciences, Bhubaneswar
• Treatments: Clozapine

Criteria

Inclusion Criteria:

• Patients clinically diagnosed with treatment-resistant schizophrenia (TRS) (TRRIP consensus criteria).

• Patients aged 18-60 years of either sex.

• Patients giving voluntary written consent for participation in the study

Exclusion Criteria:

• Patient already on Clozapine or ECT.

• History of psychoactive substance abuse or dependence.

• Co-morbid psychiatric, major medical, or neurological disorders.

• History of organicity or significant head injury.

• Pacemaker or metal in any part of the body excluding the mouth.

• Pregnant and breastfeeding females.