Comparison of Magnesium Sulphate vs Tramadol as Adjuvants in Intrathecal Bupivacaine for Postoperative Pain in TURP Patients

• Status: COMPLETED
• Trial end date: 2025-04-30

Summary

The goal of this clinical trial is to determine whether adding magnesium sulfate or tramadol to intrathecal bupivacaine improves postoperative pain control and hemodynamic stability in adult male patients undergoing transurethral resection of the prostate (TURP).

The main questions this study aims to answer are:

Does the addition of magnesium sulfate or tramadol prolong the duration of postoperative analgesia compared to bupivacaine alone?

Does either adjuvant provide better intraoperative hemodynamic stability?

Researchers will compare two groups:

One group receiving magnesium sulfate plus bupivacaine

Another group receiving tramadol plus bupivacaine

to see which combination is more effective for pain control and hemodynamic outcomes.

Participants will:

Receive spinal anesthesia with either magnesium sulfate or tramadol added to bupivacaine.

Be monitored during surgery for heart rate, blood pressure, and other vital signs.

Be assessed after surgery for pain levels and time until first request for additional pain medication.

• Phase: PHASE4

Details

• Lead Sponsor: Armed Forces Institute of Urology, Rawalpindi
• Treatments: Magnesium Sulfate; Tramadol