Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
In the management of acute coronary syndromes with ST-segment elevation (STEMI), early
analgesia reduces the effects of hyperadrenalism which increases the size of myocardial
infarction. In order to reduce pain intensity, the recommendations advocate emergency use of
morphine. In STEMI patients, other analgesic treatments could provide analgesia that is at
least as effective as morphine. The equimolar oxygen/nitrous oxide mixture (MEOPA) is widely
used in emergency medicine and has minor secondary effects that are very rapidly reversible
when inhalation is discontinued. Used in association with paracetamol, it could be an at
least equally effective alternative to the use of morphine.