Comparison of Low Volume PEG-Asc and Lower Volume PEG-Asc With Bisacodyl

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Recently a low-volume polyethylene glycol containing ascorbic acid (PEG-Asc) formulation has proven as safe and effective as traditional 4-L PEG solutions for colonoscopy preparation. However, currently available aqueous purgative formulations are poorly tolerated. The aim of this study was to compare a split-dose 2-L PEG-Asc and a 1-L PEG-Asc with bisacodyl (10 mg) formulation to determine the quality of bowel cleansing and patient tolerability.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Korea University Anam Hospital
• Treatments: Ascorbic Acid; Bisacodyl

Criteria

Inclusion Criteria:

• All patients between the ages of 20 and 75 years who were scheduled to undergo colonoscopy

Exclusion Criteria:

• aged more than 75 years.

• known or suspected gastrointestinal obstruction, Ileus

• severe heart failure

• uncontrolled hypertension (systolic pressure > 170 mmHg, diastolic pressure > 100 mmHg)

• severe constipation

• clinically significant electrolyte abnormalities

• any prior bowel resection, or significant gastroparesis.