Comparison of Low Against High Regimen of Proton Pump Inhibitors for Treatment of Acute Peptic Ulcer Bleeding

• Status: Withdrawn
• Trial end date: 2021-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Evaluate the efficacy of Two different regimens of proton pump inhibitors High against Low in the management of acute peptic ulcer bleeding

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Damascus Hospital
• Treatments: Omeprazole; Proton Pump Inhibitors

Criteria

Inclusion Criteria:

• High risk ulcers defined according to the Forrest classification With respect to high-risk stigmata,

• active bleeding was defined as a continuous blood spurting (Forrest IA)

• oozing (Forrest IB) from the ulcer base.

• A non-bleeding visible vessel at endoscopy was defined as a discrete protuberance at the ulcer base(Forrest IIA).

• An adherent clot was one that was resistant to forceful irrigation or suction (Forrest IIB).

Exclusion Criteria:

• ulcer was malignant

• non ulcerative bleeding such as angiodysplasia , a Mallory-Weiss tear....