Overview

Comparison of Intravenous Injection of Calcium Antagonist and Beta-blockade on Endothelial Shear Stress of Coronary Artery

Status:
Unknown status

Trial end date:
2010-12-01

Target enrollment:

Participant gender:

Summary

Both calcium channel antagonist and beta-blocker have cardioprotective effect. Endothelial shear stress is predictive factor of clinical outcomes in patients with obstructive stenosis. The present study aims at comparing the re-distribution of shear stress and blood velocity during whole cardiac cycle after trans-coronary injection of Nicardipine and esmolol.

Phase:

Phase 4

Details

Lead Sponsor:

Nanjing Medical University

Treatments:

Calcium Channel Blockers
Calcium, Dietary
Esmolol
Nicardipine