Comparison of Intrathecal Versus Epidural Fentanyl on Fetal Bradycardia in Labor Combined Spinal Epidural Analgesia
Status:
Recruiting
Trial end date:
2023-10-31
Target enrollment:
Participant gender:
Summary
There have been studies reporting that combined spinal-epidural (CSE) with fentanyl and
bupivacaine produce fetal bradycardia, (M.Kuczkowski, 2004) (Abrão K, 2009 ). It is unknown
whether any differences in risk exist between fentanyl and bupivacaine when used as a part of
the CSE procedure. Some authors have reported cases of parturients who developed uterine
hyperactivity and fetal bradycardia after subarachnoid administration of fentanyl during
labor. (D'Angelo & Eisenach, 1997) (Friedlander JD, 1997). It has been suggested that uterine
hypertonus, leading to non-reassuring fetal heart rate tracings, might be an etiologic factor
in these situations. (Landau, 2002).
We propose this study to test the hypothesis that administration of epidural fentanyl is
associated with a lower incidence of fetal bradycardia compared to intrathecal fentanyl.