Comparison of Fluoxetine Versus Citalopram Therapy to Control Postmenopausal Vasomotor Syndrome

• Status: Completed
• Trial end date: 2021-12-20
• Target enrollment: 0
• Participant gender: Female

Summary

This study determined the efficacy of non-hormonal therapy with citalopram compared to fluoxetine, for the treatment of menopausal symptoms in Mexican women with vasomotor syndrome (VMS) and urogenital syndrome.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Regional 1o de Octubre
• Collaborators: National Polytechnic Institute, Mexico; Universidad Nacional Autonoma de Mexico
• Treatments: Citalopram; Fluoxetine

Criteria

Inclusion Criteria:

• Participants who attended the climacteric consultation for the first time, without prior treatment of menopausal symptoms, and who met postmenopausal criteria.

• Participants who met the criteria for vasomotor syndrome and score greater than 15 points in total MRS.

• Participants without psychiatric pathology (psychiatric illnesses such as major depression, generalized anxiety disorder, among others).

• Participants who agreed to participate and gave their written informed consent.

Exclusion Criteria:

• Participants who had contraindications to receive serotonin reuptake inhibitors (SSRIs).

• Participants who were receiving prior treatment for the postmenopausal or vasomotor syndrome.

• Participants who did not agree to participate or sign the informed consent.