Comparison of Exparel to Bupivacaine With Dexamethasone in TAP Block
Status:
Terminated
Trial end date:
2015-06-06
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the efficacy and duration of bupivacaine
extended-release liposome injection (Exparel) versus bupivacaine with dexamethasone in
transversus abdominis plane (TAP) blocks for patients undergoing abdominal surgery at Emory
University Hospital and Emory University Hospital Midtown.
The investigators hypothesize that Exparel will provide greater postoperative pain relief
than bupivacaine with dexamethasone. The investigators plan to enroll up to 50 male and
female subjects meeting inclusion and exclusion criteria who will be randomized to receive
either Exparel (Group 1) or bupivacaine with epinephrine and dexamethasone (Group 2) in the
TAP block to achieve at least 22 subjects in each group