Comparison of Efficacy of Triple Regimen Based on Clarithromycin VS Metronidazole in Children
Status:
Recruiting
Trial end date:
2022-09-14
Target enrollment:
Participant gender:
Summary
All children from 1day to 18years of age, diagnosed with peptic ulcer disease due to H pylori
at Pakistan Institute of Medical Sciences, Islamabad, from July 2020 to December 2021 will be
included in the study. After informed written consent from parents/ guardians patients' bio
data along with history and examination will be recorded on a proforma. They will be
allocated into two groups, group A and group B randomly based on treatment regimen offered.
Group A: Amoxicillin AMO + Clarithromycin CLA + Proton pump inhibitor PPI) Group B:
Amoxicillin AMO+ Metronidazole MET+ Proton pump inhibitor PPI The history will include
presenting symptoms along duration, remission of symptoms after therapy and clinical outcome
will also be recorded.