Comparison of Efficacy of Intra-articular Morphine vs Methylprednisolone in Patients With Knee Osteoarthritis.
Status:
Withdrawn
Trial end date:
2018-12-31
Target enrollment:
Participant gender:
Summary
Prospective randomized double-blind controlled study. Participating patients with knee pain
secondary to knee osteoarthritis will be randomized to either the DepoMedrol 40mg + 0.25%
Bupivacaine (total Volume 5 ml) vs Morphine 3mg group+0.5% Bupivacaine (total volume 5ml) for
their intra-articular knee injection. Before the injections, baseline values of NRS
(Numerical rating scale) and WOMAC (Western Ontario and McMaster Universities Osteoarthritis
Index) Questionnaire will be recorded by investigator. After the injections NRS and WOMAC
will be recorded at 30mins and on discharge. Patient will be contacted by phone to assess the
effectivity of block or any side effects on day 1, 7,30 and 45, information including NRS (at
rest and household activity), WOMAC, supplemental analgesic, Side effects (pruritus,
paresthesia, urinary retention, nausea, vomiting, dizziness, rash) will be obtained from the
patient at the above time intervals. follow up visit will be scheduled 60days after the
procedure for re-evaluation.