Comparison of Efficacy of Cefotaxime, Ceftriaxone, and Ciprofloxacin for the Treatment of SBP in Patients With LC
Status:
Completed
Trial end date:
2018-06-01
Target enrollment:
Participant gender:
Summary
Spontaneous bacterial peritonitis (SBP) is one of the most serious complications of liver
cirrhosis. Mainstay of treatment for SBP is use of proper antibiotics. Although, several
antibiotics including cefotaxime, ceftriaxone, or ciprofloxacin are being used, it is unclear
which drug is most effective. Our aim of study is to compare the efficacy of the three
current antibiotics for the treatment of SBP in patients with liver cirrhosis.
The primary hypothesis is that the efficacy of all the antibiotics will not significantly
different. This is non-inferiority trial.