Overview

Comparison of Different Doses of Oestrogen Therapy for Preventing Intrauterine Adhesion

Status:
Completed
Trial end date:
2016-08-01
Target enrollment:
0
Participant gender:
Female
Summary
This single-center,prospective,randomized,controlled trial is conducted to evaluate the efficacy of different doses of estrogen artificial periodic therapy after hysteroscopic adhesiolysis in patients with moderate-severe adhesion.
Phase:
Phase 1/Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Fu Xing Hospital, Capital Medical University
Treatments:
Dydrogesterone
Estradiol
Estrogens
Criteria
Inclusion Criteria:

1. Moderate and severe IUA according to the AFS IU adhesion scoring system (AFS 1988
version) (19) showed in Table1 (AFS scoreā‰„5);

2. Scheduled for hysteroscopic adhesiolysis;

3. Agreed to have two follow-up hysteroscopy; and

4. Written, informed consent obtained.

Exclusion Criteria:

1. Received estrogen therapy within 3 months of enrollment;

2. Suffering from leiomyoma, polyps, cancer, or polycystic ovarian syndrome (PCOS);

3. History of genital tuberculosis; and

4. Contraindication for estrogen therapy.