Comparison of Different Botulinum Toxin A Injection Patterns in the Treatment of Blepharospasm

• Status: Unknown status
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To evaluate the efficacy of different botulinum toxin A injection patterns in treating benign essential blepharospasm and to compare their influence on condition of eye surface .

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: YangHui
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; incobotulinumtoxinA; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• had a confirmed diagnosis of bilateral BEB

• a minimum of 24-week period since the last injection was required for all patients who had previously received multiple injections of BoNT-A.

Exclusion Criteria:

• blepharospasm of known etiology (caused by medication, injury, etc.)

• history of surgical intervention for BEB (myectomy or neurectomy)

• current ophthalmologic infection

• apraxia of eyelid opening associated with levator palpebrae dysfunction