Comparison of Different Analgesia-Monitors in Tracing Unconscious Pain Sensations

• Status: Completed
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Until today there is no standard-monitoring to specifically reflect the analgesic component of general anesthesia. Quality and safety of general anesthesia are of major clinical importance and can be improved by limiting the administration of opioid analgesics to the minimum dose needed. This study therefore examines the quality of three different monitoring techniques (PhysioDoloris, MetroDoloris, Lille, France, SPI (Surgical Plethysmographic Index), GE Healthcare, Helsinki, Finland and AlgiScan, IDMed, Marseille, France) in assessing the level of analgesia during general anesthesia. Therefore a standardized painful stimulus is applied under different levels of analgesic drugs. The monitor's indices are compared to clinical signs such as an increase in heart rate and blood pressure.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universitätsklinikum Hamburg-Eppendorf
• Treatments: Remifentanil

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists Status I and II

• > 18 years

• Elective surgery in Urology/Ear Nose Throat under general anesthesia without the use of muscle relaxants

Exclusion Criteria:

• Diseases with impairment of sensitivity (diabetes, gout, polyneuropathy, peripheral arterial obstructive disease)

• Beta blocker and digitalis therapy

• Chronic pain therapy

• Pacemaker therapy

• Dermal diseases with affection of the forearm/hand