Comparison of Corticosteroid Injection, Nighttime Splinting, or Their Combination for Initial Treatment of Moderate-to-Severe Carpal Tunnel Syndrome

• Status: NOT_YET_RECRUITING
• Trial end date: 2027-07-15

Summary

The goal of this clinical trial is to compare the efficacy of corticosteroid injection, night splinting, and their combined use as initial treatments for adults with moderate to severe carpal tunnel syndrome (CTS), and to assess the safety and tolerability of these interventions. The primary research questions include:

• Doe corticosteroid injection, night splinting, and their combined use as initial treatments reduce the need for surgery in participants with moderate to severe CTS?
• How do these interventions affect the improvement of patient symptoms?

Participants will:

• Receive corticosteroid injection, night splinting, or their combination as initial treatments.
• Visit the clinic once every 6 weeks over a period of one year for assessments and dynamic adjustment of the treatment plan.
• Undergo periodic assessments of wrist function, quality of life, and sleep quality using standardized questionnaires.

• Phase: NA

Details

• Lead Sponsor: Yun Qian
• Collaborator: Shanghai 6th People's Hospital
• Treatments: Adrenal Cortex Hormones; Steroids