Overview

Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery

Status:
Completed
Trial end date:
2019-03-27
Target enrollment:
Participant gender:
Summary
Regional anesthesia is commonly used for elective and emergency cesarean delivery. It provides numerous safety advantages when compared to general anesthesia for both the mother and fetus1. Epidurals also have the added benefit of being able to provide pain relief throughout labor and in the event of cesarean delivery, epidural analgesia can be "extended" to provide surgical anesthesia. Numerous studies have been performed to assess the onset times of various local anesthetics when administered through an epidural catheter. Attempts to reduce anesthetic onset time and improve the quality of intraoperative analgesia have been attempted by using different local anesthetic solutions and by the addition of other drugs to the epidural solution (such as epinephrine, fentanyl and sodium bicarbonate).
Phase:
Early Phase 1
Details
Lead Sponsor:
University of Arkansas
Treatments:
Chloroprocaine
Epinephrine
Epinephryl borate
Fentanyl
Lidocaine
Procaine
Racepinephrine