Comparison of Carvedilol and Atenolol on Anti-anginal and Metabolic Effects in Patients With Stable Angina Pectoris

• Status: Completed
• Trial end date: 2013-08-01
• Target enrollment: 0
• Participant gender: All

Summary

There are few data regarding anti-anginal effects between beta-blockers with and without vasodilating property. Beta-blocker without vasodilating property is generally known to have unfavorable effects on glucose and lipid metabolism. Therefore, the investigators compared carvedilol and atenolol on anti-anginal and metabolic effects in patient with stable angina pectoris.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Gachon University Gil Medical Center
• Treatments: Atenolol; Carvedilol

Criteria

Inclusion Criteria:

• Stable angina pectoris who had a positive exercise treadmill test according to the American College of Cardiology Foundation and the American Heart Association guidelines

Exclusion Criteria:

• Acute coronary syndrome

• Coronary revascularization within the past 3 months

• Asthma or chronic obstructive lung disease

• Bradycardia (heart rate < 55 beat/min)

• History of severe adverse reaction to beta-blockers

• Symptomatic arrhythmia requiring anti-arrhythmia therapy

• Heart failure

• Severe renal or hepatic failure